First, we will examine the difference between hemp and cannabis, chemically, medicinally, and legally. Next, we will do a brief overview of just what the endocannabinoid system is, and how it is involved in the skin, and explore recent scientific studies behind cannabinoids and skin conditions. Other characteristically painful skin conditions that are not as frequently encountered include pyoderma gangrenosum, hidradenitis suppurativa, calciphylaxis, and vasculitis. Included in this course will be a summary of what skin care and topical pain products are already on the market, and what bright options the future holds.