Dyspareunia, can be classified into superficial dyspareunia. Superficial dyspareunia can be associated with vaginal dermatosis, atrophic vaginitis, vulvovaginitis, and vulvodynia, whereas deep dyspareunia is commonly caused by endometriosis, adhesions, fibroids, and cervicitis. Dyspareunia can be found along with interstitial cystitis, irritable bowel syndrome, and/or sexual abuse. This lecture will discuss many of the myths associated with sexual pain and how sexual pain fits the biopsychosocial model of pain. Useful to all healthcare providers, a comprehensive Guidelinefor the evaluation and management of this disorder will be formulated.